Feller moved from her native Switzerland to France in 1835 to be a missionary. For many years she worked with Louis Roussy, eventually founding a church in Marieville. In 1838 the church was destroyed and Henriette threatened by an angry mob. Feller continued her work, however, and in 1854 opened the Institut Feller at Longueuil for the education of girls. The school expanded to admit boys in 1840. that same year, Feller helped found the Societe missionaire franco-canadiene (the French Canadian Missionary Society). The school was formally incorporated as the Evangelical Society of Grande-Ligne in 1855,